Businesses for Sale in Columbia, Missouri

Service Businesses

Join the leading franchise in residential and commercial painting services with 34 years of experience. This opportunity allows entrepreneurs to establish their own protected territory in Columbia, MO. With two business models available—subcontracted or employee crews—franchisees benefit from high profit margins and minimal overhead. The average annual revenue per location is approximately $2.1 million. The initial franchise fee is $65,000, with a total investment starting at $171,000. This franchise is recognized as the top choice by industry publications, providing extensive marketing support and training for new owners.

Education & Children

Here's your chance to own a top-tier sports training academy in two Missouri locations. Company operates 24 teams that train together and compete. Four additional teams will be added in 2026 resulting in $160k in additional revenue. Through it's two facilities, it provides instruction, batting cages, camps and private instruction. The company targets children from 8 to 18 years old and focuses on both baseball and softball. Expertise in collegiate recruiting having 150 athletes committed. Owner/Manager willing to stay engaged in the business with new owner. Decrease is 2025 revenue resulted from offering athletes an 9 month payment plan in addition to the existing 3 and 6 month payment plans.

Online & Technology

Fully remote business with significant growth potential and operational leverage (100% REMOTE / MOTIVATED SELLER / $330K SDE | $250K of EBITDA) Established, trusted digital traffic intermediary platform connecting major global brands with high-intent traffic across home services, insurance, finance, education, legal, and e-commerce sectors. Premier client roster includes some of the largest and most recognizable companies in the world, consistently delivering measurable results for enterprise-scale clients with significant advertising budgets and high performance standards. Operates as a performance-based traffic intermediary, linking advertisers with a vetted network of 2,000+ affiliate marketers across social, native, search, display, email/SMS, push, and SEO channels. Over 2 million verified leads and 500+ brands promoted since 2016 - powered by a lean, tech-driven infrastructure using Affise (tracking) and Tipalti (payments) for seamless global operations. Fully remote, low-overhead model that can be managed from anywhere - no office, minimal fixed costs, and highly scalable. Recurring, diversified revenue streams built on CPL, CPA, CPS, CPI, and Rev-Share models that align incentives and drive predictable growth. Exceptional opportunity for a digital agency, performance marketer, or investor seeking a scalable, high-ROI online business with elite clients, strong margins, and significant upside through automation and vertical expansion.

Automotive & Boat

A used car dealership in Columbia, Missouri, features an on-site repair shop, specializing in reliable pre-owned vehicles and affordable repair services. This business generates revenue from both sales and service, offering convenience and value to customers while maintaining strong community connections.