Businesses for Sale in Portland, Maine

Restaurants & Food

Roll in the dough! This business is ready to go! Dominant pizza restaurant space positioned in the heart of Portland with a solid lease. Prominently situated on Exchange St, the primary retail and tourist venue in Maine. Locate here in one of Maine’s busiest areas. This leased space awaits your operational touch. Excellent frontage on Exchange St with over 26,190 pedestrians/day. Features include a bar, pizza oven, natural gas, and on-site seating.

Manufacturing

This is a compelling opportunity to acquire a Tier 3 Adult-Use cannabis cultivation facility in South Portland, Maine, complete with an established wholesale account base and a rapidly growing presence across the state. Since its first harvest in May 2024, the business has quickly scaled operations and distribution, generating approximately $1.868 million in 2025 revenue while securing placement in a growing number of licensed retail stores throughout Maine. The facility spans 11,100 sq. ft., including 3,250 sq. ft. of dedicated cultivation space, and has been built out as a state-of-the-art cultivation operation. The cultivation layout includes four flower rooms, one mother room, and one veg room, supported by recently installed modern lighting and dozens of new genetics. The operation is powered by robust infrastructure, including 1,200 amps of 480V and 120/208V three-phase power, providing efficiency, scalability, and reliability. Investment Highlights Tier 3 Adult-Use Cultivation License Established wholesale distribution network Approximately $1.868M in 2025 revenue Over $5 million invested into the business, including approximately $3 million in facility buildout, equipment, infrastructure, and operational improvements Manufacturing license application submitted, creating potential for vertical integration and additional revenue streams 12-month option to purchase the building from the landlord, providing a potential path to real estate ownership Turnkey operation with substantial infrastructure already in place Significant growth potential in Maine’s expanding adult-use cannabis market Maine continues to be an attractive cannabis market with strong wholesale demand and a growing adult-use sector. This business is well-positioned to capitalize on that demand through its premium flower quality, respected brand reputation, and expanding operational capabilities. Financial Snapshot 2025 Revenue: $1,868,000 Facility Details Total Facility Size: 11,100 sq. ft. Cultivation Space: 3,250 sq. ft. Ceiling Height: 12′ Flower Rooms: 4 Mother Rooms: 1 Veg Rooms: 1 Veg Lighting: 6 dual-tier benches with 38 Philips grid lights Lease & Utilities Rent: $18,315/month Lease Type: NNN Lease Term: 10-year lease commenced January 1, 2021 Power: 1,200 Amp | 480V | 120/208V | 3-Phase Licenses Adult-Use Tier 3 Cultivation License – Licensed to cultivate, harvest, package, and transfer cannabis products to licensed cannabis retailers, manufacturers, and other authorized operators in accordance with Maine regulations. Asking Price $1,490,000.00 (Seller Open to Offers with $750k Down) Must sign an NDA/Waiver before any other detailed information is released, along with the company’s location. This listing is Fully Exclusive only by Green Life Business Group, Inc. Green Life Business Group, Inc DRE CA LIC# 02061374 Drew Mathews, DRE LIC CA# 02091143 If you have any questions call Drew (619) 653-0483 Email: ceo@glbgroupinc.com Green Life Business Group Inc . we are here to both help you sell or buy a cannabis business. National Affiliate Listings This listing is represented by (Local Broker) via the Green Life Business Group National Affiliate Program.

Health Care & Fitness

This is a franchise listing. This upscale wellness and aesthetics clinic delivers a full suite of anti-aging, detox, and body-enhancement treatments, combining clinical expertise with a spa-like experience. The sale includes all furniture, equipment, and inventory—making it a true turnkey opportunity. The core focus is on lymphatic and digestive detoxification along with advanced body sculpting services. Using proprietary, results-oriented methods, the clinic helps clients improve their health from the inside out. As a brand solely focused on lymphatic wellness, it has carved out a unique niche and built a strong, loyal customer base—97% of whom are women. Clients report noticeable results such as decreased bloating and water retention, improved digestion, toxin release, and visible body contouring improvements—all within a relaxing, high-end environment designed to promote restoration and well-being. The business operates on a cash-pay model with a high average transaction size and consistent recurring revenue driven by memberships. It can be managed semi-absentee, and comprehensive training and ongoing corporate support are provided. No medical or aesthetic background is necessary—strong leadership and an interest in health and wellness are what matter most. Opportunities for multi-unit growth are also available in the area.