Businesses for Sale in San Antonio, Texas

Restaurants & Food

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Health Care & Fitness

This long-standing general practice in northwest San Antonio has been operational for over 40 years, generating annual collections of $462,000 from three fully equipped operatories. The patient base of 941 is built solely on referrals and reputation, with no external marketing efforts or HMO plans. The practice features four operatories, including one additional operatory that is built but not equipped, allowing for expanded capacity without renovations. A new CBCT has been installed, facilitating in-house procedures for implants and endodontics. The commercial property can be purchased separately for those interested in owning the building. The current payer mix is favorable, providing a solid foundation for future growth.

Health Care & Fitness

This well-established veterinary practice generates over $1.19M in revenue with a 14% profit margin. The included real estate boasts excellent visibility on a bustling community street, and there are no after-hours emergency duties, promoting a healthy work-life balance. The current owner is open to assisting during the transition to maintain client and staff continuity. San Antonio is rapidly growing, projected to reach a population of 1.57 million by 2026, marking a 9% increase since 2020, with a steady growth rate of 1.5% annually. This opportunity offers a strong foundation with a loyal client base, diverse exotic cases, and significant potential for expansion.

Health Care & Fitness

This well-established dental practice in a historic building in San Antonio, Texas, boasts over 30 years of patient loyalty and features cutting-edge technology, including CBCT and an in-house lab. Perfect for a new doctor, the practice offers a solid financial history that supports 100% bank financing, ensuring a seamless transition to ownership with minimal initial investment. The new owner will inherit a comprehensive patient base covering general dentistry, clear aligners, sedation, and implants, along with dedicated seller support to maintain goodwill. There are also significant growth prospects by increasing the current four-day workweek, enhancing digital marketing strategies, and expanding high-margin surgical services to quickly build equity.

Financial Services

This well-established Allstate agency, operating for over 30 years in the thriving Northeast San Antonio area, has cultivated strong customer relationships and a solid local reputation along the I-35 Corridor. With annual revenues of $267,060 from a written premium book valued at $2.84 million, the agency manages 1,071 policies and boasts an impressive retention rate of 81.74%. An experienced team, including a bilingual staff member, is ready to ensure a seamless transition for the new owner. The office space is available, and there may be seller financing options for eligible buyers. This agency presents a remarkable opportunity for those looking to expand on a strong foundation in the growing markets of San Antonio, Schertz, Cibolo, Garden Ridge, and New Braunfels.

Financial Services

This lucrative portfolio of 141 ATMs is on the market for $369,000. It includes 18 Managed ATMs and 123 Processing-only ATMs located in San Antonio and nearby areas. Managed by third parties or store owners, this portfolio offers a straightforward operating experience and a reliable source of recurring income. Key details include an asking price of $369,000, with monthly net revenues of $2,442.88 from Processing ATMs and $4,609.11 from Managed ATMs, totaling $7,052 monthly. The route requires minimal labor, as management is handled by others. The ATMs are strategically placed in locations like convenience stores, markets, hotels, dispensaries, and game rooms. This portfolio is perfect for both seasoned operators and newcomers, boasting impressive numbers and significant growth potential in Texas.

Retail

This well-established health and nutrition store caters to a dedicated local clientele with premium products and exceptional service. It boasts a menu of healthy foods, smoothies, and an on-site kitchen for grab-and-go meals and specialty items, fostering repeat visits and customer loyalty. This venture presents a fantastic opportunity for an owner-operator to expand and elevate the business further.

Pet Services

<p>SMALL ANIMAL PRACTICE WITH REPRODUCTIVE SERVICES SPECIALTY<br />San Antonio Metro Area, Texas</p><p>A 40+ year community veterinary practice with a differentiated reproductive services specialty is available in one of Texas's fastest-growing metro areas. The practice comes with an experienced, long-tenured support team, a standalone facility on nearly an acre of land, and a client base built over decades of service.</p><p>The practice is a full-service small animal GP generating $950,000 to $1.1M in annual revenue with 7 team members, including technicians with 13 and 16 years of tenure. The facility is a 4,300+ square foot standalone building on approximately 0.85 acres. Real estate is owner-occupied and available for purchase or lease.</p><p>The reproductive services specialty sets this practice apart from a typical GP. Capabilities include progesterone testing, surgical and transcervical insemination, semen collection and shipping, and ultrasound confirmation. For a buyer with interest or training in reproductive medicine, this is a ready-made niche that most practices simply do not offer.</p><p>The practice is currently operating below full capacity, giving a full-time veterinarian immediate opportunity to increase production by expanding appointment availability and restoring the full range of services. New clients continue to present each year, reflecting sustained demand in a growing San Antonio-area market. The facility, equipment, staff, and client relationships are all in place.</p><p>This practice is well suited for an associate veterinarian ready to step into ownership. Veterinary-specific lenders offer 100% financing for qualified DVMs.</p><p>To receive the full practice profile, financial details, and transaction terms, please contact Veterinary Sales &amp; Consulting to execute a Non-Disclosure Agreement.</p>

Service Businesses

An outstanding opportunity to acquire a highly successful and market-leading franchise location of a premier, nationally recognized staffing organization. This established business provides comprehensive staffing and workforce solutions, connecting qualified employees with regional employers while offering robust recruiting, payroll support, and workforce management services. As one of the largest and most successful territories within a well-regarded national franchise network, this operation boasts significant scale, a dominant local market presence, and a highly efficient, established infrastructure. A primary competitive advantage of this business is the extensive back-office and administrative support provided by the franchisor. The franchisor handles payroll and payment processing for the temporary workforce, dramatically reducing administrative burdens and complex back-office overhead. This streamlined operational model enables local leadership to focus almost exclusively on high-value activities: building client relationships, business development, recruiting, and day-to-day operations. The business has secured a dominant market position through longstanding client relationships, an excellent reputation for reliable service, and a proven ability to recruit and manage a substantial temporary and contract workforce. With a seasoned management team already in place to assist with a smooth ownership transition, this mature, highly profitable operation is primed for continued growth.

Pet Services

<p>Owner-Operator Opportunity | Small-Animal Practice, San Antonio Metro, TX | $684,086 Revenue</p><p>Veterinary Sales &amp; Consulting is pleased to present a 17-year small-animal general practice located in the San Antonio metro area. The practice generated $684,086 in gross revenue in 2025, supported by an established client base and a long-tenured support staff. The clinic operates from a 2,800 square foot leased retail facility in a high-traffic corridor, offering strong daily visibility and accessibility. The facility includes three exam rooms, a surgical suite, in-house laboratory, and digital radiography.</p><p>Ownership has elected to list this practice at a price meaningfully below the Broker Opinion of Value to support a clean, timely transition to a qualified buyer-veterinarian. The practice is configured as an owner-operator opportunity. Real estate is leased and not included in the sale; a long-term lease is available and assignable at closing. Support staff is in place and expected to remain through and beyond transition.</p><p>Qualified buyers may execute a Non-Disclosure Agreement to receive the full Confidential Information Memorandum, normalized financials, and supporting documentation. Email us @ <a>info@Vetsalesconsulting.com</a></p><p></p>

Health Care & Fitness

Award-Winning Fitness Business Sale Price: $650,000.00 Location: San Antonio, Texas Business Overview This is a unique opportunity to acquire an established, award-winning personal training and wellness studio that has built an outstanding reputation for delivering individualized fitness, nutrition, and wellness programs. Unlike traditional gyms, this business focuses on personalized, science-based programs designed to help clients achieve lasting results through professional guidance and customized training. The studio has been recognized multiple times as one of the top fitness facilities in San Antonio and continues to attract a loyal and diverse client base. Products & Services Individual and semi-private personal training Customized nutrition and weight-management programs Metabolic and VO₂ Max testing In-Body body composition analysis Individual and small-group yoga and mobility training Cryotherapy and recovery services Virtual and remote training programs Corporate wellness programs Motivational speaking and educational programs Specialized athlete performance programs Key Highlights Award-winning fitness and wellness studio Multiple revenue streams beyond traditional personal training Degreed, certified, and experienced wellness professionals State-of-the-art metabolic testing and body composition technology Medical-grade equipment and advanced recovery services Established reputation for personalized fitness and nutrition programs Flexible business model with both in-studio and remote training options Strong opportunities for future expansion Growth Opportunities This business is positioned for significant growth through the expansion of virtual training, corporate wellness programs, athletic performance services, recovery therapies, nutritional consulting, and additional wellness offerings. The diverse service model creates multiple opportunities to increase revenue while serving a broad range of clients, from fitness enthusiasts and athletes to individuals seeking medically supported wellness programs. An Exceptional Acquisition Opportunity Ideal for a fitness professional, entrepreneur, healthcare provider, wellness organization, or investor seeking a recognized brand with multiple revenue streams, a proven business model, and outstanding opportunities for continued growth and expansion.

Beauty & Personal Care

Located in an affluent, high-traffic neighborhood, this well-established nail salon presents a rare opportunity for an owner-operator or investor looking to enter or expand in the beauty industry. The salon boasts a loyal, repeat clientele and an excellent reputation for cleanliness, professionalism, and quality service. The spacious 1,600 sq. ft. facility is thoughtfully designed and exceptionally well maintained. It features: • 8 manicure stations • 10 pedicure chairs • 2 private treatment rooms – ideal for waxing, facials, lashes, or massage • Upscale interior with modern finishes • Fully staffed with experienced professionals The business is profitable and efficiently run but still offers significant upside potential for a motivated buyer. Growth opportunities include: • Hiring additional nail technicians to meet demand • Introducing new services such as lashes, facials, or massage • Launching a marketing strategy — the salon currently has no website or social media presence, representing a major opportunity to attract new clients and increase brand awareness This can be a turnkey operation by hiring replacements for the sellers, everything else is in place for a seamless transition. Whether you're an experienced salon owner or an entrepreneur looking for a high-potential venture, this business offers stability, style, and room to grow in a highly desirable market.

Beauty & Personal Care

Rare opportunity to acquire a profitable, well-established spa serving an upscale market in Bexar County, TX. Ideally located in a high-income residential area with convenient highway access, this turnkey business offers an outstanding platform for a buyer seeking entry into or expansion within the beauty, skincare, and aesthetics space. This elegant, fully staffed facility operates smoothly and offers a diverse menu of in-demand services, including facials, spa treatments, body services, and medical aesthetics. The current owner maintains a semi-absentee role, allowing a new owner the flexibility to remain hands-on or continue operating with management and staff in place. The spa benefits from a strong and loyal repeat clientele while also generating approximately 250 new clients per month, reflecting both its reputation and continued market demand. With Seller’s Discretionary Earnings of approximately $277,000 last year, this business is designed to offer an attractive return on investment in approximately 2 to 3 years.

Automotive & Boat

Business is offered at $1,000,000 with real estate available for an additional $1,000,000 This is an opportunity to acquire a full-service auto repair business with associated real estate in a growing Texas market. The business has an established customer base and generates consistent revenue from a mix of repeat retail clients and general repair work. Based on the updated recast, the business is producing approximately $312,000 in Seller’s Discretionary Earnings (SDE) on projected 2025 performance, with revenue growing from ~$644K in 2021 to ~$974K in 2025. Gross margins have improved over time, currently around 70%+, with net income of approximately $197K. The business is owner-operated with technicians handling day-to-day service work. Operations are straightforward and include general automotive repair and maintenance. There is no heavy reliance on a single customer or contract. The facility is fully equipped with standard shop equipment, including lifts, diagnostic tools, and work bays. The real estate is included in the sale, providing control of the location and eliminating lease risk. This deal is likely not SBA lendable due to the structure of the financials and reliance on owner involvement and add-backs. A buyer should be prepared to complete the purchase with cash or a combination of cash and seller financing. There is room for growth through increased marketing, additional fleet work, expanded hours, or operational improvements, but the business as it stands is stable and cash-flowing. The business and real estate are offered together, making this a straightforward acquisition for a buyer looking for an operating shop with an established base and real estate included. Offered at $1,000,000 for the business and $1,000,000 for the real estate, this opportunity combines immediate profitability with long-term real estate ownership. It is well-suited for an experienced operator looking to take advantage of a turnkey operation with strong cash flow, or for an investor who wants to secure both a profitable business and valuable property in one transaction.

Automotive & Boat

Business is offered at $750,000 with real estate available for $800,000 This is an established used car dealership located in San Antonio, operating with a straightforward model focused on pre-owned vehicle sales. The business generates revenue primarily through retail sales, with some leasing activity, and operates from an existing customer base with systems already in place. In 2025, the dealership is on pace to generate approximately $2.27M in gross sales with about $553K in gross profit. Net profit is approximately $79K, with Seller’s Discretionary Earnings (SDE) of $132,435 after add-backs. SDE has declined from prior years (over $300K in 2021–2022), reflecting margin compression and higher operating costs. The business carries approximately $300K in vehicle inventory at cost, which supports current sales volume. The real estate is included in the overall opportunity and is valued at $800,000, with the business being offered at $750,000. This is best suited for an owner-operator who can improve margins through tighter expense control, better inventory management, or increased sales volume. Based on current financial performance, the deal is likely not SBA lendable.

Restaurants & Food

Own one of San Antonio's most recognized and respected Greek restaurants. For forty years, this restaurant has built a loyal following by serving authentic Greek cuisine prepared with traditional family recipes and an unwavering commitment to quality. The restaurant is known for offering one of the most extensive Greek menus in the city and has earned an outstanding reputation for both exceptional food and customer service. The restaurant's famous homemade salad dressing has become a customer favorite and is available in grocery stores across Texas and several states, creating additional brand recognition beyond the restaurant itself. This family-owned restaurant was built on a lifelong dream of bringing authentic Greek flavors and hospitality to Texas. Today, it remains a beloved dining destination for both longtime customers and first-time visitors. Products & Services Authentic Greek cuisine prepared from traditional family recipes One of the most extensive Greek menus in San Antonio Signature homemade salad dressing distributed through well-known grocery stores throughout Texas Lunch and dinner service Live entertainment featuring music and belly dancing on select evenings A welcoming, family-friendly dining experience Key Highlights Established for forty years Loyal, multigenerational customer base Recognized for exceptional food and service Strong local brand recognition Featured by newspapers, magazines, radio, and television Consistently recognized as one of the top Greek restaurants in San Antonio Popular live entertainment that creates a unique dining experience The restaurant has received extensive media coverage and has been recognized by local publications as one of the best Greek restaurants in San Antonio. An Exceptional Acquisition Opportunity Ideal for a restaurateur, hospitality group, or entrepreneur seeking an established, profitable restaurant with a loyal customer base, a recognizable brand, and a rich history of serving authentic Greek cuisine in the San Antonio market. The owner is retiring but wants to keep the legacy alive with a new owner.

Restaurants & Food

Location: San Antonio, Texas Business Overview Own a modern, fully equipped Taiwanese-inspired tea house and specialty café offering one of today's most popular beverage concepts. This established business combines premium handcrafted drinks, fresh food offerings, and the convenience of a drive-thru, creating multiple revenue streams and a loyal customer base. Beautifully designed and completely turnkey, this business is ready for a new owner to continue its success from day one. Products & Services Premium Taiwanese Boba Tea Fresh Brewed & Milk Teas Specialty Hot & Flavored Teas Fruit Refreshers & Smoothies Slushies Specialty Coffee & Espresso Drinks Lattes & Matcha Beverages Authentic Vietnamese Bánh Mì Sandwiches Light Specialty Food Offerings Key Highlights Established and loyal customer base Excellent reputation for quality and customer service Multiple revenue streams with strong growth potential Opportunity to expand catering, delivery, online ordering, and additional menu offerings Facilities & Atmosphere Customers enjoy a warm, inviting atmosphere while choosing from a wide variety of tasty beverages and fresh specialty foods. The efficient layout, modern equipment, and drive-thru capability provide an outstanding customer experience while supporting efficient day-to-day operations. An Exceptional Acquisition Opportunity Ideal for an owner-operator, entrepreneur, restaurant group, or investor seeking a profitable, turnkey café with immediate operating income, a proven concept, and outstanding opportunities for future growth.

Restaurants & Food

This is an established Mediterranean and Middle Eastern food truck business located in San Antonio, Texas. The business specializes in shawarma, gyros, grilled meats, chicken and beef rice bowls, lamb bowls, falafel, hummus, and other popular halal-style street food items. Founded in 2022, the business has built a local customer base by offering fresh, flavorful food, generous portions, and friendly service. The concept serves a popular and growing food category, appealing to customers looking for authentic Middle Eastern and Mediterranean street food. The business has produced consistent annual revenue, with gross receipts of approximately $334,000 in 2024 and $348,000 in 2025, along with strong year-to-date 2026 performance. Operations are straightforward, with a small employee base and the seller willing to provide transition training to a new owner. This opportunity may be attractive to an owner-operator, family buyer, or food-service entrepreneur looking for an established mobile food business with an existing customer base, recognizable menu, and potential growth opportunities through expanded hours, catering, delivery platforms, events, social media marketing, and additional locations or trucks.

Service Businesses

Offering mobile screen manufacturing, repair, and solar shading solutions to residential and commercial clients in San Antonio, this business provides a convenient service directly to customers. With a focus on quality and efficiency, supported by proprietary software and an internal call center, this opportunity in the home improvement sector stands out in the market. The owner is selling due to resource limitations and the need for additional resources to meet market demand. The business operates from a leased property and is homebased, not a franchise resale opportunity.