Businesses for Sale in Greenville, South Carolina

Building & Construction

No Installer Payroll | Key Staff Stay | Franchise Support This franchise resale is an established residential flooring sales and installation business operating three territories across four counties in South Carolina's Upstate. Rather than a retail storefront, the business runs on in-home design consultations — a fully stocked sample vehicle brings the showroom to the customer, so they see real materials in their own light, against their own furniture. No storefront to staff, no inventory on the shelf, no waiting on foot traffic. Customers respond to the model: 5.0 on Google across more than 115 reviews. Installation runs entirely through a vetted subcontractor network — seven-plus crews covering hard surface, tile and stone, carpet, refinishing, and specialty coatings, plus shower and bathroom renovation. No installers on payroll. Labor scales with the schedule instead of sitting on the books during slow weeks. The operations and production manager and a design associate with seven years in the flooring trade both intend to stay with the new owner. Territory rights are secured and producing. More than 550 leads came through in the most recent full year, roughly a third from referral and organic sources. The Upstate remains one of the fastest-growing housing markets in the Southeast. - Three territories spanning four counties - 5.0 Google rating across 115+ reviews - No installer payroll — established multi-crew subcontractor network - Key operations and sales personnel staying through the transition - National brand, training, and lead generation systems in place - Wrapped sample vehicle and two complete sample sets - Builder association, chamber, and B2B referral relationships active - No retail location, no inventory, minimal fixed overhead Additional information available to qualified buyers upon execution of a confidentiality agreement. Contact 757-292-9930.

Health Care & Fitness

Acquire a well-established in-home care business serving the growing Greenville and Spartanburg, South Carolina market. This turnkey operation provides an excellent opportunity to enter one of the nation's fastest-growing industries with an established client base, experienced staff, and significant room for expansion. The business generated $285,000 in gross revenue during 2025 and has already billed $191,000 through June 2026. Most current business comes from Medicaid clients and word-of-mouth referrals, with very limited community marketing to date—creating substantial upside for a new owner willing to invest in business development and referral partnerships. The operation is supported by a full-time administrator who manages the day-to-day office operations, while approximately 25 to 30 caregivers provide services on an as-needed basis. This scalable staffing model allows labor costs to closely align with client demand. The exclusive territory includes Greenville and Spartanburg, serving a population of approximately 673,500 residents, with a significant and growing senior demographic that continues to drive demand for quality in-home care services. The current owner is selling due to an unexpected health diagnosis. Although they had not planned to sell, they must now focus on their health, creating an opportunity for a new owner to acquire a business with a solid foundation and tremendous growth potential. The franchisor provides comprehensive onboarding, operational training, marketing support, and ongoing business coaching to help ensure a successful transition. This opportunity is ideal for an owner-operator, healthcare professional, or entrepreneur looking to expand within the rapidly growing home healthcare industry.

Health Care & Fitness

This is a franchise listing. This upscale wellness and aesthetics clinic delivers a full suite of anti-aging, detox, and body-enhancement treatments, combining clinical expertise with a spa-like experience. The sale includes all furniture, equipment, and inventory—making it a true turnkey opportunity. The core focus is on lymphatic and digestive detoxification along with advanced body sculpting services. Using proprietary, results-oriented methods, the clinic helps clients improve their health from the inside out. As a brand solely focused on lymphatic wellness, it has carved out a unique niche and built a strong, loyal customer base—97% of whom are women. Clients report noticeable results such as decreased bloating and water retention, improved digestion, toxin release, and visible body contouring improvements—all within a relaxing, high-end environment designed to promote restoration and well-being. The business operates on a cash-pay model with a high average transaction size and consistent recurring revenue driven by memberships. It can be managed semi-absentee, and comprehensive training and ongoing corporate support are provided. No medical or aesthetic background is necessary—strong leadership and an interest in health and wellness are what matter most. Opportunities for multi-unit growth are also available in the area.

Health Care & Fitness

This listing features a veterinary practice located in Greenville, South Carolina, offering a unique opportunity for prospective buyers. Interested parties should review the terms of the Confidentiality and Non-Disclosure Agreement (NDA) to learn more about this business opportunity.

Restaurants & Food

This is a unique chance to own a well-established upscale restaurant located in Downtown Greenville, SC, known for its elegant dining experience in a vibrant restaurant and entertainment hub. The chef-driven establishment features a blend of European fine dining and South American flavors, offering premium steaks, seafood, and a diverse dinner menu alongside a well-crafted beverage program. Catering to various meal times including lunch, dinner, and brunch, the restaurant generates multiple revenue streams. It also provides private dining options, special events, and a unique dinner-club experience, setting it apart from typical dining venues. The business has built a strong reputation for exquisite cuisine and attentive service in a refined yet inviting setting. This opportunity is ideal for a seasoned restaurateur, chef-owner, hospitality group, or investor looking for a fully operational restaurant in Greenville, SC, without the extensive costs and time needed to establish a new high-end venue. The restaurant boasts a professionally designed ambiance suitable for both casual meals and special events. With existing infrastructure, kitchen equipment, and operational systems, the new owner will benefit from significant savings in both capital and time compared to starting from scratch. The location is strategically positioned within one of South Carolina's most bustling dining and entertainment districts, catering to locals, professionals, tourists, and visitors attending cultural events. The restaurant's upscale offerings, combined with private dining and catering services, enhance its market appeal. While the competitive restaurant landscape in Downtown Greenville poses challenges, the established operations and multiple revenue channels provide a solid foundation for new ownership. There are numerous avenues for growth, including increasing private dining bookings, corporate events, and enhancing marketing efforts. An experienced operator could also explore expanding brunch offerings, special events, and high-margin dining experiences.

Health Care & Fitness

Deal Highlight: Owner-Managed Fitness Studio - Three Year SDE Average of $212,813 - Selling Price $530k - SBA Preapproved - No Seller Note Are you looking for a lucrative investment opportunity in the fitness industry? Look no further than this established Fitness Enterprise located in the Upstate of South Carolina. With a solid foundation and a proven track record of success, this business is now available for sale, presenting you with an exciting opportunity to take over and continue its legacy of promoting health and wellness in the community. This thriving gym business is situated in a high-traffic area, attracting a loyal and diverse clientele, from business professionals to retirees. Boasting state-of-the-art equipment, modern facilities, and a large team of experienced trainers, this gym has earned a reputation for providing top-notch service and achieving impressive results for its members. One of the key strengths of this business is its loyal and dedicated customer base. The gym has cultivated a strong community of members who not only value the quality of the facilities and services offered but also appreciate the supportive and motivating environment created by the staff. With a focus on personalized fitness programs and ongoing support, this gym continues to attract new clients through positive word-of-mouth referrals. Furthermore, the potential for growth in this business is virtually limitless. South Carolina is a thriving market for fitness and wellness services, with an increasing emphasis on health-conscious lifestyles. By leveraging the existing reputation and infrastructure of the gym, there is ample opportunity to expand the business through targeted marketing campaigns, innovative fitness programs, and strategic partnerships with local health and wellness businesses. This Business checks all the boxes and is ready for a new owner to step in and take it to new heights. Don't miss out on this exceptional opportunity to own a successful fitness business in a prime location. Visit our website at https://www.tworld.com/westerncarolinas to learn more about this exciting investment opportunity and take the first step towards becoming the proud owner of this thriving gym business in South Carolina. Contact us today to schedule a consultation and discover how you can be a part of this dynamic and lucrative industry.

Health Care & Fitness

Deal Structure: $150,000, includes an estimated $110,000 in Assets. Owner is willing to familiarize the new owner for Two Weeks. Are you ready to invest in a Franchise Fitness business in the heart of South Carolina? Look no further! We are excited to present to you an incredible opportunity to acquire a well-established Fitness Gym in South Carolina that is sure to make you break a sweat - in the best way possible. This Fitness Gym business, located in a prime location has been serving its dedicated clientele for over a decade. With a solid reputation for providing top-notch fitness services, state-of-the-art equipment, and a welcoming atmosphere, this gym has become a go-to destination for fitness enthusiasts in the area. The gym has built strong relationships with its members, who appreciate the personalized attention, diverse fitness programs, and supportive community that the gym provides. With a focus on customer satisfaction and results-driven approaches, this gym has cultivated a loyal following that keeps coming back for more. But that's not all! The potential for growth in this business is immense. There is ample opportunity to expand services, introduce new fitness programs, and tap into additional revenue streams. Whether it's adding specialized classes, partnering with local businesses for corporate wellness programs, or incorporating technology for virtual training sessions, the possibilities for growth are endless. By acquiring this established Fitness Gym business, you are not just buying a business - you are investing in a lifestyle. Imagine the satisfaction of helping individuals achieve their fitness goals, building a stronger and healthier community, and being a part of an industry that is only growing in demand. Don't miss out on this exciting opportunity to take over a successful fitness business in South Carolina. This business is ready for a new owner to step in, bring fresh ideas, and take it to new heights of success. So, if you are passionate about fitness, ready to make a positive impact, and eager to be part of a dynamic industry, then this Fitness Gym business is waiting for you to make your mark. For more information and to explore this incredible opportunity further, visit our website at https://www.tworld.com/westerncarolinas. Take the first step towards owning your own fitness empire today!

Health Care & Fitness

Are you looking to invest in a thriving health and wellness business? Look no further than this established Fitness Yoga Studio in South Carolina, United States. With a successful track record and a loyal client base, this business presents an exciting opportunity for potential buyers. Located in a bustling community, this Fitness Yoga Studio has been in operation for a year and has already made a name for itself as a go-to destination for fitness enthusiasts in the area. The studio offers a variety of yoga classes for all levels, making it appealing to a wide range of clients, from beginners to experienced yogis. One of the key strengths of this business is its loyal and dedicated client base. The studio has built a strong reputation for its welcoming environment, experienced instructors, and high-quality classes. Many clients have been attending regularly, contributing to a stable revenue stream. Furthermore, the Fitness Yoga Studio has shown promising growth potential. With the increasing popularity of yoga and fitness activities, there is a great opportunity to expand the business further and attract new clients. The current owner has laid a solid foundation for success, making it a prime time for a new owner to take the business to the next level. By acquiring this Fitness Yoga Studio, you will inherit not only a running business but also a supportive community of clients who value health and wellness. The studio is fully equipped with all the necessary yoga props and equipment, making it a turnkey opportunity for a new owner. You also receive the Social Media Accounts and Customer Lists associated with the Business, to support your Marketing Efforts. If you have a passion for health and wellness and are looking to make a sound investment in a growing industry, this Fitness Yoga Studio is the perfect fit for you. Take advantage of this chance to own a successful business with a strong foundation and endless potential for growth. Don't miss out on this exciting opportunity to step into the thriving health and wellness sector. Visit our website at https://www.tworld.com/ to learn more about this Fitness Yoga Studio business for sale in South Carolina. Contact us today to schedule a viewing and start your journey towards becoming the proud owner of this fantastic business.

Retail

Bring All Offers! Seller Highly Motivated, looking to Relocate ASAP. Price of $150,000 includes the Inventory. Seller is willing to negotiate the price. Owner Operated Vape and Tobacco Business on one of the Busiest Roads in Greenville County. Your Business Revenue made $290k in Sales in 2025. You want to be a Business Owner with a Business that actually makes sense, an Owner who can train you, and a Low Entry Point. Your Business has a High Traffic Location! Loyal Client Base! Huge Potential! Monthly Financial Records show that $7000 Net Profit per month is easily achieved for the owner, and has been as high as $10,000 Net. This is a unique shop with custom art work, high quality products, and excellent vendors. Low rent store has room for lounging area or other retail possibilities. The shop is clean and organized. Customers are rewarded for their continued business through a competitive Loyalty Program. You make money in this industry, and especially this store! The Business has a strong presence Online and through Social Media, including a Google Business Profile, Facebook, Instagram, and more! Inventory is around $40,000 Owner's cost and is included in the Selling Price. NDA and Buyer Profile Required. Tours will be scheduled by Broker. Contact Eli Tatem for details! 864-527-5995, etatem@tworld.com

Restaurants & Food

Well-established Italian Restaurant located in Upstate South Carolina. This is a Hand-On Business for an Owner who likes to cook Pizza and Pasta! With a small intimate staff, the overhead is low and the Profits are high! With roughly 4 years at the current location, this restaurant is a prime opportunity waiting for the right buyer. Situated on a bustling street in a rapidly growing town, this restaurant boasts a stellar reputation that draws in loyal customers day in and day out. Operating 6 days a week, this eatery is a beloved staple in the community, known for its authentic Italian cuisine and warm, welcoming atmosphere. What sets this restaurant apart is its strategic location amidst new housing developments and apartments, offering a captive audience of potential patrons. Despite its success, the business currently does little to no advertising, representing a significant growth opportunity for a savvy entrepreneur to capitalize on the demand in the area. The town's upcoming projects, including a stadium just a few miles away and an amphitheater nearby, promise to bring even more foot traffic and visibility to this already thriving restaurant. With the right marketing strategy, the potential for expansion and increased revenues is limitless. For aspiring restaurateurs, this business presents a chance to step into a turnkey operation with a solid foundation and a dedicated customer base. Don't miss out on this exciting opportunity to own a piece of culinary history in a town on the rise. Contact Eli Tatem for more information and take the first step towards making this Italian Restaurant yours. He'll set up your personal tour. Act now and savor the taste of success with this remarkable business venture.

Retail

This well-regarded interior design firm, operational for two decades, specializes in high-end residential projects and offers a comprehensive service from consultation to installation. With a strong presence in two Southeastern markets and a network of remote designers, the company serves both local and national clients. It provides a range of products including furniture, lighting, rugs, and custom furnishings, catering mainly to affluent homeowners while occasionally handling commercial projects. The business operates from two showrooms totaling over 5,000 sq. ft. and is supported by a dedicated team of around 15 staff members. The current owner, who is nearing retirement, is willing to assist the new owner for up to a year to ensure a smooth transition. This opportunity is listed at $1,900,000, with identified growth potential through enhanced e-commerce, digital marketing, and partnerships with independent designers.