Businesses for Sale in Myrtle Beach, South Carolina

Health Care & Fitness

This is a franchise listing. This upscale wellness and aesthetics clinic delivers a full suite of anti-aging, detox, and body-enhancement treatments, combining clinical expertise with a spa-like experience. The sale includes all furniture, equipment, and inventory—making it a true turnkey opportunity. The core focus is on lymphatic and digestive detoxification along with advanced body sculpting services. Using proprietary, results-oriented methods, the clinic helps clients improve their health from the inside out. As a brand solely focused on lymphatic wellness, it has carved out a unique niche and built a strong, loyal customer base—97% of whom are women. Clients report noticeable results such as decreased bloating and water retention, improved digestion, toxin release, and visible body contouring improvements—all within a relaxing, high-end environment designed to promote restoration and well-being. The business operates on a cash-pay model with a high average transaction size and consistent recurring revenue driven by memberships. It can be managed semi-absentee, and comprehensive training and ongoing corporate support are provided. No medical or aesthetic background is necessary—strong leadership and an interest in health and wellness are what matter most. Opportunities for multi-unit growth are also available in the area.

Entertainment & Recreation

The Asher Theatre and Conference Center is a multifaceted entertainment and event venue located at 3237 Waccamaw Boulevard in Myrtle Beach, South Carolina. Established in 2018 by entertainer James Stephens III, the Asher was created to provide professional, family-friendly entertainment while serving the local community and tourism market. The venue features live theatrical and musical entertainment, including Stephens’ signature Man of a Thousand Voices production and the popular Motown ’59 musical revue. Beyond entertainment, the facility operates as a conference and event center with six conference rooms, a theater with professional stage and sound capabilities, and space suitable for corporate meetings, training programs, private events, banquets, weddings and community functions. The leased facility also accommodates multiple independent subtenants, creating recurring rental income that helps offset the property's occupancy expenses. There is no actively operating kitchen in the facility although there is room for one. The Dinner Theaters are catered by local catering services.

Retail

This specialty retail boutique offers a carefully curated selection of home décor, gifts, furnishings, artwork, and lifestyle products in one of Horry County's premier shopping destinations. Combining retail sales with design-inspired merchandising, the business has built a loyal customer following and strong local reputation while providing significant opportunities for continued growth.

Building & Construction

Situated in the rapidly growing and highly sought-after Myrtle Beach area, this established outdoor living business boasts nearly $1,000,000 in average annual sales. Specializing in crafting functional and beautiful outdoor spaces, the company has a strong base of repeat clients and is poised for further growth. The owner is also offering real estate for sale at an additional price.

Service Businesses

Operating successfully for over 30 years in the Myrtle Beach area, this plumbing business in Horry County, SC, is a profitable venture. Specializing in residential services, with some commercial projects, the company serves new homes and maintains relationships with past customers. With a dedicated team of 12+ employees and a full-time office manager, the business is experiencing annual sales growth. The owner, deeply involved in operations, is willing to support the new owner for a year. Situated in a prime location with ample parking, the business has significant growth potential.

Restaurants & Food

This oceanfront restaurant in Myrtle Beach features a unique interior decor, outdoor patio with ocean views, and a full liquor license. Situated near the Myrtle Beach Boardwalk, this turnkey establishment benefits from strong tourist and local foot traffic year-round.

Beauty & Personal Care

This sale includes ~$150k in raw materials for jewelry that will generate enough finished product to last decades! Estimated retail value in excess of $400k. The owner works 11 hours per week with a dedicated team and includes a strong provable component of cash income. This business is well established, comprised of four separate full-service tattoo and body-piercing studios known for bold custom work, strict hygiene standards, and a loyal local following. The shop delivers a wide range of tattoo styles—from traditional and realism to black-and-gray and custom lettering—paired with professional piercing services using single-use, medical-grade equipment. The studio benefits from repeat clientele, walk-in traffic, and strong word-of-mouth referrals. Artists operate in a clean, well-organized workspace designed for both comfort and efficiency, supporting steady daily productivity. Retail add-ons (aftercare products, jewelry upgrades) can add to revenues when appropriately structured. Elastic Financing: The seller will allow the buyer to make seasonally adjusted payments.